Zhen Ma

Assistant Professor, Samuel and Carol Nappi Research Scholar

Biomedical & Chemical Engineering

Education:

  • Postdoc, University of California, Berkeley
  • Ph.D. Clemson University
  • M.S. Tianjin University
  • B.S. Tianjin University

Research Interests:

  • Developmental biology and tissue morphogenesis
  • Cardiac tissue engineering and regenerative medicine
  • Stem cell engineering

Current Research:

Human induced pluripotent stem cells (hiPSCs) allows the recapitulation of human disease models in vitro, which can be used to both study disease mechanisms and ultimately design and screen personalized therapeutics prior to large animal or clinical trials. My research focuses on developing multi-scale cardiac models through the combination of stem cell biology, micro/nanotechnology and cardiovascular research. These in vitro models help us not only understand a variety of fundamental questions on cardiac physiology and development, but also improve the diagnosis and treatment for human heart diseases.

Teaching Interests:

  • Stem cell engineering

Honors:

  • American Heart Association Postdoctoral Fellowship
  • Siebel Institute Postdoctoral Fellowship
  • Fellow Award of Biomedical Engineering Society, Cellular and Molecular Bioengineering Group

Recent Publications:

Mathur A., Ma Z., Loskill P., Jeeawoody S., and Healy K.E. (2016) “In vitro cardiac tissue models: current status and future prospects” Advanced Drug Delivery Reviews 96:203-13.

Ma Z., Wang J., Loskill P., Huebsch N., Koo S., Svedlund F.L., Marks N.C., Hua E., Grigoropoulos C.P., Conklin B.R., and Healy K.E. (2015) “Self-organizing cardiac microchamber mediated by geometric confinement” Nature Communications 6: 7413.

Ma Z., Koo S., Finnegan M.A., Loskill P., Huebsch N., Marks N.C., Grigoropoulos C.P., Conklin B.R., and Healy K.E. (2014) “Three-dimensional filamentous human diseased cardiac tissue model” Biomaterials 35(5): 1367-77.