Biomedical & Chemical Engineering
- 318 Bowne Hall
- [email protected]
- Research Scientist, Washington University in Saint Louis
- Postdoctoral Fellow and Instructor, Saint Louis University
- Postdoctoral Associate, Virginia Tech
- Ph.D., Indian Institute of Technology Kanpur, India, 2011
- Bachelor’s in Pharmacy, India, 2004
- Syracuse Biomaterials Institute
- Targeted and programmed drug delivery
- Injectable and biodegradable hydrogels and scaffolds
- Musculoskeletal tissue engineering
Inflammation is a primary component of all diseases, including several musculoskeletal disorders such as arthritis. My research focuses on engineering immunomodulatory biomaterials for advancing the treatment of musculoskeletal disorders and related inflammatory disorders. We are particularly interested in the design of macrophage targeting and programmed drug delivery systems for spatially and temporally controlled biomolecule release to regulate inflammation. We employ a combination of in vitro models and pre-clinical animal models to evaluate the translational potential of these novel delivery systems.
- Drug Delivery
- E. Jain, N.Chinzei, A. Blanco, N. Case, L. J. Sandell, S. Sell, M. F.Rai, S. P. Zustiak, Sustained release of platelet-rich plasma from polyethylene glycol hydrogels exerts beneficial effects on chondrocytes, J. Orthop. res. (https://doi.org/10.1002/jor.24404)
- S.H. Huang, S. Sheth, E. Jain, X. Jiang, S.P. Zustiak, L. Yang, Whispering gallery mode resonator sensor for in situ measurements of hydrogel gelation, Opt Express 26 (2018) 51-62.
- E. Jain, A.S. Qayyum, G. Kolar, Y. Kim, S.A. Sell, S.P. Zustiak, Design of electrohydrodynamic sprayed polyethylene glycol hydrogel microspheres for cell encapsulation, Biofabrication 9 (2017) 025019.
- E. Jain, S. Sheth, S. Patel, M. Flanagan, Q. Gan, S.A. Sell, A.M. Montano, S.P. Zustiak, Injectable microgels development for sustained GALNS enzyme replacement therapy for Morquio syndrome type A, Mol Genet Metab 120 (2017) S70-S70.
- E. Jain, S. Sheth, A. Dunn, S.P. Zustiak, S.A. Sell, Sustained release of multicomponent platelet-rich plasma proteins from hydrolytically degradable PEG hydrogels, J Biomed Mater Res A 105 (2017) 3304-3314.
- E. Jain, L. Hill, E. Canning, S.A. Sell, S.P. Zustiak, Control of gelation, degradation and physical properties of polyethylene glycol hydrogels through the chemical and physical identity of the crosslinker, J Mater Chem B 5 (2017) 2679-2691.
- S.G. Priya, A. Gupta, E. Jain, J. Sarkar, A. Damania, P.R. Jagdale, B.P. Chaudhari, K.C. Gupta, A. Kumar, Bilayer Cryogel Wound Dressing and Skin Regeneration Grafts for the Treatment of Acute Skin Wounds, ACS Appl Mater Inter 8 (2016) 15145-15159.